FDA: Non-Aspirin Painkillers Even In Small Amounts Can Kill You

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As far back as 2005 the FDA advised that non-aspirin nonsteroidal anti-inflammatory drugs, or NSAIDs, could up the risk of heart attack and stroke.

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The watchdog agency is now boosting that warning, noting that drugs like ibuprofen (often sold under the Motrin IB brand), naproxen (Aleve), and celecoxib (Celebrex) may pose a risk even in small amounts and that these drugs should be used sparingly and for short periods, the New York Times reports. (Aspirin, although an NSAID, doesn’t pose the same risk, but does carry some of its own, the FDA notes.)

Although an FDA review found that higher doses increased the risk of heart attack or stroke—and the risk may increase with length of use—”there is no period of use shown to be without risk,” an FDA deputy director says. And while people with cardiovascular disease are more at risk for being adversely affected by NSAIDs, “everyone may be at risk—even people without an underlying risk for cardiovascular disease,” the FDA rep says.

NSAIDs decrease production of prostaglandins, chemicals spewed out after an injury that trigger inflammation, WNCNreports. Per the FDA review, over-the-counter NSAIDs could up the risk of heart attack and stroke by about 10%, low-dose prescription meds by 20%, and higher-dose prescription NSAIDs by 50%, with “significant variability” in each estimate, an Emory University medical professor tells the Times.

One NSAID, Vioxx, was taken off shelves in 2004 after being linked to 140,000 heart attacks over a five-year period, Bloomberg notes. The director of Northwestern University’s Center for Communication and Health says that “one of the underlying messages (is) there are no completely safe pain relievers, period.”

How to cut down on potential NSAID risks, per the Harvard Health Blog: Take the lowest dose that works, limit how long you take it, and never take more than one NSAID at once.

In case you missed it read about how Rick Santorum major donor in 2012 suggested that women should put aspirin between their knees to prevent pregnancy.

Source: Newser

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Professor Mike

Professor Mike is a left-leaning, dog loving, political junkie. He has written dozens of articles for Substack, Medium, Simily, and Tribel. Professor Mike has been published at Smerconish.com, among others. He is a strong proponent of the environment, and a passionate protector of animals. In addition he is a fierce anti-Trumper. Take a moment and share his work.
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8 years ago

[…] FDA: Non-Aspirin Painkillers Even In Small Amounts Can Kill You(madmikesamerica.com) […]

8 years ago

[…] FDA: Non-Aspirin Painkillers Even In Small Amounts Can Kill You […]

8 years ago

It’s all about who you believe. Remember the too many eggs will kill you thing? How about mayo is deadly? I’ve been using ibuprofen for years and I’m healthy as a horse.

8 years ago

Oh no. What am I going to do now. I get terrible headaches and can’t take aspirin either.

8 years ago

I knew of this after learning it several years ago. I rarely ever took NSAIDS so it wasn’t an issue for me. Good public service posting this Mike.

8 years ago

I’ve a bad back and take tons of Ibuprofen, because aspirin messes up my stomach. I didn’t know any of this. Thanks Mike.

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