Key depression gene identified
American scientists have identified a gene that appears to play a key role in the onset of depression, a finding which may help researchers develop new treatments. A team from Yale University found that a gene called MPK-1 is twice as active in those who suffer from depression. The gene works as an “off-switch,” they say, controlling a “cascade” of chemicals needed for healthy brain function, the AFP notes.
“This could be a primary cause, or at least a major contributing factor, to the signaling abnormalities that lead to depression,” the study’s lead author tells the Telegraph. Scientists compared tissue samples from 21 dead patients who were diagnosed with depression to samples from depression-free individuals. Subsequent tests on mice confirmed a link. (Click here to read more about depression and dementia.)
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The Lawyer
October 18, 2010 at 12:12 pm
I used to think that depression was something that a person could control with their outlook on life, but have since learned from watching This Emotional Life on PBS that it is a full-on disease. This confirms that. I also learned that I have never been depressed, just bummed out at times.
Mother Hen
October 18, 2010 at 12:14 pm
I too think what I have is a mood disorder, not true depression, as it seems affected by light more than anything else. I’m wondering if some UV hemp lights might brighten the mood a bit better…
Holte Ender
October 18, 2010 at 3:55 pm
Days without sunshine can affect my mood. This is why pre-Christian Pagens had big mid-winter festivals (Christmas) to brighten up the days of little sun.