Paralyzed Dogs Walk After Nose Cell Transplant

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Jasper. Pic courtesy of The Times Health News

Scientists have reversed paralysis in dogs after injecting them with cells grown from the lining of their nose.  I wonder what science will be doing 100 years from now?

Well, a group of paralyzed dogs is walking again—with a little help from a harness—after scientists injected cells from the dogs’ noses into the injured portion of their spinal cords. The procedure could eventually help paralyzed humans regain some degree of movement, researchers say, though they caution that such a feat is a long way off. In the experiment, scientists in Britain took olfactory ensheathing cells from the noses of dogs whose back legs were nonfunctional after injury. The olfactory system is the only site where adults continue to develop nerve fibers, the BBC notes.

After growing the removed cells in a lab, the scientists injected them into 23 pet dogs while injecting a neutral control substance into 11 others. The latter group saw no improvement, but many of the 23 transplant dogs were able to walk again, aided by a harness on a treadmill. “We’re confident that the technique might be able to restore at least a small amount of movement in human patients with spinal cord injuries,” says a researcher. “But that’s a long way from saying they might be able to regain all lost function.”

What are olfactory ensheathing cells:

The only part of the body where nerve fibers continue to grow in adults is the olfactory system.

Found in the at the back of the nasal cavity, olfactory ensheathing cells (OEC) surround the receptor neurons that both enable us to smell and convey these signals to the brain.

The nerve cells need constant replacement which is promoted by the OECs.

For decades scientists have thought OECs might be useful in spinal cord repair. Initial trials using OECs in humans have suggested the procedure is safe.

Many thanks to the BBC for their contributions to this story.

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Professor Mike

Professor Mike is a left-leaning, dog loving, political junkie. He has written dozens of articles for Substack, Medium, Simily, and Tribel. Professor Mike has been published at Smerconish.com, among others. He is a strong proponent of the environment, and a passionate protector of animals. In addition he is a fierce anti-Trumper. Take a moment and share his work.
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11 years ago

As the saying goes, “You ain’t seen nothing yet.”

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